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There exists also an increased danger of seizure next discontinuation of thienodiazepines. Medications which reduce the seizure threshold which include tramadol must be averted throughout withdrawal.

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Even so, depending on its structural similarity to other triazolo-BZDs, it has been meant the potency of flunitrazolam is higher than in the presently extremely strong flunitrazepam [151]. A t ½ of all around eight hours in oral fluid is documented [87]. There aren't any further more facts on its pharmacological and/or toxicological profile thus far. Flunitrazolam is just not now managed underneath the 1971 United Nations Convention on Psychotropic Substances or the 1961 Solitary Conference on Narcotic Prescription drugs.

A2: Precise dosing makes sure regular leads to research, important for correct data Investigation and conclusions.

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